Research Profiles: Chip-based mosaic immunoassays
نویسندگان
چکیده
منابع مشابه
Micromotor-based lab-on-chip immunoassays.
Here we describe the first example of using self-propelled antibody-functionalized synthetic catalytic microengines for capturing and transporting target proteins between the different reservoirs of a lab-on-a-chip (LOC) device. A new catalytic polymer/Ni/Pt microtube engine, containing carboxy moieties on its mixed poly(3,4-ethylenedioxythiophene) (PEDOT)/COOH-PEDOT polymeric outermost layer, ...
متن کاملFabrication of phospholipid bilayer-coated microchannels for on-chip immunoassays.
Herein we describe a new class of microfluidic immunoassays based upon solid supported lipid bilayers. Two-dimensionally fluid bilayer material, which can accommodate multivalent binding between surface-bound ligands and aqueous receptors, was coated on the surface of poly(dimethylsiloxane) microchannels. The bilayers contained dinitrophenyl (DNP)-conjugated lipids for binding with bivalent ant...
متن کاملMagnetic-Nanoparticle-Based Immunoassays-on-Chip: Materials Synthesis, Surface Functionalization, and Cancer Cell Screening
and dormant cancer cell, [ 12 ] are often rare in a mixture of heterogeneous cells (usually less than 1% of the total cell number). The low number of target cells in blood sample largely limits the detection capability and reduces effectiveness of the time-sensitive cancer treatment. Therefore, the isolation and detection of the rare cells for early diagnosis and prognosis of cancers have drawn...
متن کاملOn-chip native gel electrophoresis-based immunoassays for tetanus antibody and toxin.
By integrating photopolymerized cross-linked polyacrylamide gels within a microfluidic device, we have developed a microanalytical platform for performing electrophoresis-based immunoassays. The microfluidic immunoassays are performed by gel electrophoretic separation and quantitation of bound and unbound antibody or antigen. To retain biological activity of proteins and maintain intact immune ...
متن کاملResearch of Image Mosaic Algorithm Based on Harris Corner Detection
This paper studies the general steps and methods of the image matching technology. Using a set of optimized Harris corner detection algorithm, a similar measure extracting feature points by the maximum correlation coefficient to achieve accurate matching. Finally, the weighted smoothing is performed to realize the seamless splicing of the two images according to the bilinear interpolation of th...
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ژورنال
عنوان ژورنال: Analytical Chemistry
سال: 2001
ISSN: 0003-2700,1520-6882
DOI: 10.1021/ac012385p